Meeting Banner
Abstract #0640

The Limbic System in Asperger Syndrome: A Preliminary Diffusion Tensor Imaging Tractography Study

Luca Pugliese1,2, Michel Thiebaut de Scotten1,2, Stephanie Ameis2, Flavio Dell'Acqua1,2, Eileen Daly1, Declan Murphy1, Marco Catani1,2

1Phsychological Medicine, section of Brain Maturation, Institute of Psychiatry, London, UK; 2Natbrainlab, section of Brain Maturation, Institute of Psychiatry, London, UK


It has been suggested that people with Autistic Spectrum Disorder (ASD) have altered development (and connectivity) of limbic circuits. However, direct evidence is lacking. We used DTI-tractography to compare, in vivo, tract-specific measurements along the principal limbic pathways between subjects with Asperger syndrome and healthy controls.