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Abstract #0664

DTI of the Kidney at 3T - Protocol Evaluation, Reproducibility and Comparison to 1.5T

Mike Notohamiprodjo1, Annie Horng1, Ulrike Attenberger1, Olaf Dietrich1, Henrik J. Michaely2, Karin A. Herrmann1, Maximilian F. Reiser1, Christian Glaser1

1Institute for Clinical Radiology, University Hospitals Munich, Munich, Bavaria, Germany; 2Institute for Clinical Radiology, University Hospital, Mannheim, Bavaria, Germany

The purpose of this study was to assess the feasibility of DTI of the kidney at 3T. Mean Fractional Anisotropy (FA)-values at 3T were not significantly different to 1.5T-measurements. Signal-to-noise-ratio and contrast-to-noise-ratio for cortex and medulla were significantly higher at 3T. However, medullary FA was less reproducible than FA of the cortex and 1.5T-measurements provided slightly lower Apparent diffusion coefficient (ADC)-values. For calculation of FA, acquisition of 2 b-values and 6 diffusion-directions appeared sufficient. DTI of the kidney may become a valuable tool for studying renal microarchitecture, however a certain field-strength associated variability and varying reproducibility should be considered.