Abstract #0806

Multi-Color 19F CSI: Simultaneous Detection of Differently Labeled Cells in Vivo

Thomas Christian Basse-Lsebrink^1,2, Gesa Ladewig¹, Thomas Kampf^2,3, Gerd Melkus², Daniel Haddad⁴, Wolfgang Rudolf Bauer³, Peter M. Jakob^2,4, Guido Stoll¹

¹Neurology, University of Wrzburg, Wrzburg, Germany; ²Department of Experimental Physics 5, University of Wrzburg, Wrzburg, Germany; ³Medical Clinic and Polyclinic I, University of Wrzburg, Wrzburg, Germany; ⁴Research Center for Magnetic Resonance Bavaria (MRB), Wrzburg, Germany

¹⁹F markers provide unambiguous signal in vivo due to the low natural abundance of fluorine in living organisms. A further advantage of 19F molecular MRI is that fluorine markers possess a unique spectral signal. Therefore, chemical shift imaging (CSI) methods can be used to distinguish between cells labeled with different fluorine markers.