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Abstract #0806

Multi-Color 19F CSI: Simultaneous Detection of Differently Labeled Cells in Vivo

Thomas Christian Basse-Lsebrink1,2, Gesa Ladewig1, Thomas Kampf2,3, Gerd Melkus2, Daniel Haddad4, Wolfgang Rudolf Bauer3, Peter M. Jakob2,4, Guido Stoll1

1Neurology, University of Wrzburg, Wrzburg, Germany; 2Department of Experimental Physics 5, University of Wrzburg, Wrzburg, Germany; 3Medical Clinic and Polyclinic I, University of Wrzburg, Wrzburg, Germany; 4Research Center for Magnetic Resonance Bavaria (MRB), Wrzburg, Germany

19F markers provide unambiguous signal in vivo due to the low natural abundance of fluorine in living organisms. A further advantage of 19F molecular MRI is that fluorine markers possess a unique spectral signal. Therefore, chemical shift imaging (CSI) methods can be used to distinguish between cells labeled with different fluorine markers.