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Abstract #0817

In Vivo Validation of Fast Cine DENSE MRI for the Quantification of Regional Cardiac Function

Li Feng1, Robert M. Donnino2, James Babb3, Leon Axel4, Daniel Kim4

1Biomedical Enginnering, Polytechnic Institute of New York University, Brooklyn, NY, USA; 2Medicine, NYU Langone Medical Center, New York, NY, USA; 3Radiology, NYU Langone Medical Center, New York, NY, USA; 4Center for Biomedical Imaging and Radiology, NYU Langone Medical Center, New York, NY, USA

Accurate assessment of cardiac function plays an important role in the management of heart disease. Quantitative assessment of regional cardiac function may additionally improve the accuracy of detecting subtle wall motion abnormalities due to heart disease. Recently, fast cine displacement-encoded (DENSE) MRI was developed to produce relatively high quality strain maps within clinically acceptable breath-hold duration of 12 cardiac cycles . While this pulse sequence is promising for clinical applications, it has not been validated. Therefore, the purpose of this study was to validate the relative accuracy of fast cine DENSE MRI in controls and patients with heart disease.