Abstract #0969

In Vivo Visualization of Cerebellar Cortical Layers Using Structural High Field MRI

Jos Pedro Marques¹, Wietske van der Zwaag¹, Cristina Granziera², Gunnar Krueger³, Rolf Gruetter¹

¹Centre d'Imagerie BioMdicale, CIBM, Ecole Polytechnique Fdrale de Lausanne, Lausanne, Vaud, Switzerland; ²Department of Neurology and Radiology, Centre Hospitalier Universitaire Vaudois, CHUV, Lausanne, Vaud, Switzerland; ³Advanced Clinical Imaging Technology, Siemens Medical Solutions-CIBM, Lausanne, Vaud, Switzerland

The highly complex geometry and small size of the cerebellum make this area particularly attractive for very high-resolution imaging. With the use of a surface coil at 7T, human in-vivo cerebellum images with an in-plane resolution of 120m were acquired. At this spatial resolution, ~240m structures within the cerebellar cortex could be visualized. Using the image contrast of 30m rat data acquired at 14T as a comparison, these structures could be identified as granule and molecular layers of the cerebellum.