Meeting Banner
Abstract #0969

In Vivo Visualization of Cerebellar Cortical Layers Using Structural High Field MRI

Jos Pedro Marques1, Wietske van der Zwaag1, Cristina Granziera2, Gunnar Krueger3, Rolf Gruetter1

1Centre d'Imagerie BioMdicale, CIBM, Ecole Polytechnique Fdrale de Lausanne, Lausanne, Vaud, Switzerland; 2Department of Neurology and Radiology, Centre Hospitalier Universitaire Vaudois, CHUV, Lausanne, Vaud, Switzerland; 3Advanced Clinical Imaging Technology, Siemens Medical Solutions-CIBM, Lausanne, Vaud, Switzerland

The highly complex geometry and small size of the cerebellum make this area particularly attractive for very high-resolution imaging. With the use of a surface coil at 7T, human in-vivo cerebellum images with an in-plane resolution of 120m were acquired. At this spatial resolution, ~240m structures within the cerebellar cortex could be visualized. Using the image contrast of 30m rat data acquired at 14T as a comparison, these structures could be identified as granule and molecular layers of the cerebellum.