Diagnosis of Brain Metastasis:Feasibility and Efficacy of Motion-Sensitized Driven-Equilibrium(MSDE) Turbo Spin-Echo Sequence

Eiki Nagao¹, Takashi Yoshiura¹, Akio Hiwatashi¹, Koji Yamashita¹, Hironori Kamano¹, Yukihisa Takayama¹, Osamu Togao¹, Makoto Obara², Tomoyuki Okuaki², Hiroshi Honda¹

In this study, a turbo spin-echo with a motion-sensitized driven-equilibrium (MSDE) sequence was used as an alternative head MR imaging technique for brain metastasis. We hypothesized that MSDE suppresses signals from flowing blood in vessels that can mimic the enhancement of brain metastases. Post-contrast images of 18 patients were analyzed. In each patient, images were obtained using three sequences: 3D MPRAGE, 3D turbo spin echo (TSE) without MSDE, and 3D TSE with MSDE. Our results suggest that MSDE effectively suppresses blood vessel signals from both arteries and veins, while TSE without MSDE suppresses signal from arteries only.