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Abstract #1212

Functional Connectivity Differences to Ventral Putamen of Gulf War Syndrome II and Control Subjects

Lei Jiang1, Parina Gandhi1, Mingguo Qui1, Aman Goyal1, Yan Fang1, Luo Ouyang1, Kaundinya Gopinath1,2, Wendy Ringe3, Robert Haley1,4, Richard Briggs1,4

1Department of Radiology, UTSouthwestern Medical Center, Dallas, TX, USA; 2Department of Internal Medicine, UTSouthwestern Medical Center , Dallas, TX, USA; 3Departments of Psychiatry, UTSouthwestern Medical Center, Dallas, TX, USA; 4Department of Internal Medicine, UTSouthwestern Medical Center, Dallas, TX, USA


The purpose of this study was to compare the connectivity of ventral putamen to other brain regions between two groups of Gulf War veterans (one with Haley Syndrome II and the other normal controls) with resting state fcMRI. Examination of functional connectivity to right ventral putamen during rest revealed the differences in brain function between subject Groups The results suggest that functional connectivity MRI can be used to find biomarkers for subtle diseased states such as Gulf War Illness