Abstract #1214

Adaptation of the Visual Cortex in Response to Cataract Surgery

Astrid Rosenstand Lou^1,2, Hanne Olsen Julian², Jan Ulrik Prause³, Troels Wesenberg Kjr⁴, Olaf B. Paulson¹, Kristoffer Hougaard Madsen¹

¹Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark; ²Eyeclinic, Rigshospitalet, Copenhagen, Denmark; ³Eye Pathology Institute, Rigshopitalet, Copenhagen, Denmark; ⁴Clin. Neurophysiology, Rigshospitalet, Copenhagen, Denmark

We aim to investigate the plasticity in the normal aging brain in response to an abrupt change in vision. 15 subjects with senile cataract were followed by fMRI before cataract surgery, 2 days after surgery and 6-8 weeks after surgery. Results show a tendency that the difference in BOLD activation resulting from stimulation of the operated and non-operated eye decrease over time.