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Abstract #1218

Absolute Quantification of Phosmomono- And Phosphodiesters in the Brain of Patients with Major Depression

Wolfgang Weber-Fahr1, Helga Wentzel, Traute Demirakca1, Alexander Sartorius1, Gabriele Ende1

1Neuroimaging, Central Institute of Mental Health, Mannheim, Germany

The phospholipd metabolism in a group of 18 patients and 22 matched controls was investigated with 31P-MRS. We used a 3D-whole head RINEPT Sequence together with point-spread function (PSF) corrected tissue segmentation for robust absolute quantification.