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Abstract #1238

GRAPPA-Accelerated High-Resolution Diffusion Tensor Imaging of Infants Without the Need for General Anesthesia

Stefan Skare1, Samantha Holdsworth1, Kristen Yeom1, Roland Bammer1

1Radiology, Stanford University, Palo Alto, CA, USA

Children undergoing a diffusion MRI exam are often scanned under general anesthesia, which is costly and leads to discomfort for both patient and parent. In this work we demonstrate that high-resolution diffusion imaging is possible without sedation and with the child or infant moving in the MR scanner. 3D motion correction, complex averaging, and a new GRAPPA weight set selection criteria has demonstrated motion free, high resolution and high SNR isotropic DWI images ready to use in the clinical routine.