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Abstract #1332

In Vivo Visualization of Brain Tumour Angiogenesis Using 3D δR2-Based Microscopic MR Angiography (3DδR2-MMRA)

Chien-Yuan Lin1,2, Ming-Huang Lin2, Sui-Shan Lin2, Yu-Ying Tung2, Jyh-Horng Chen1, Chen Chang2

1Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan; 2Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan

Tumor-associated microvascular changes offer important new insight into how tumors grow and respond to treatment. This study was aimed to simultaneously assess the changes of microvascular morphology and function on ethylnitrosourea(ENU)-induced rat brain tumor model at different stages using 3D GR2-Based Microscopic MR Angiography (3DGR2-mMRA).