MeiYu Yeh1, Tsong-Hai Lee2, Ho-Ling Liu3,4
1Department of Medical Imaging and Radiological Sciences, Chang Gung University,, Kwei-Shan , Tao-Yuan, Taiwan; 2Stroke Section, Department of Neurology and Stroke Center,, Chang Gung Memorial Hospital, Kwei-Shan , Tao-Yuan, Taiwan; 3Department of Medical Imaging and Radiological Sciences, Chang Gung University, Kwei-Shan, Tao-Yuan, Taiwan; 4MRI Center, Chang Gung Memorial Hospital, Kwei-Shan , Taoyuan, Taiwan
Age is the most important non-modifiable risk factor for stroke and it is estimated that the stroke rate is doubled each 10 years after age 55. Diffusion- and perfusion-weighted magnetic resonance imaging (DWI and PWI, respectively) can provide a simple and feasible method to investigate the ischemic brain tissue at risk for infarction in the acute stage of stroke. Our study suggests that the reason for aging and hypertension to be the most significant risk factors for stroke is possible that they may increase the susceptibility of normal brain tissue to ischemic injury by influencing the cerebral diffusion and perfusion.