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Abstract #1440

Model-Based Streamline Rejection for Probabilistic Tractography

Jonathan D. Clayden1, Chris A. Clark1

1Institute of Child Health, University College London, London, England, UK

This work describes a method for rejecting false positive pathways in probabilistic tractography based on a model of tract shape. Unlike with region-of-interest methods, the rejection criterion is probabilistic and based on the topology of the tract in each individual. In contrast to thresholding approaches, the method is sensitive to the meaning of the data and has no user-defined parameters. The common observation of declining visitation count with distance from a seed point is also alleviated.