Hao Huang1,2, Xin Fan1
1Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, USA; 2Department of Radiology, UT Southwestern Medical Center, Dallas, TX, USA
Tractography based on diffusion tensor imaging (DTI) provides an efficient and noninvasive means to reveal the morphology of white matter tracts. Conventional streamline method such as FACT is known to have limitation of tracing only single lines. Fast marching tractography (FMT) allows fiber crossing and branching based on DTI, but is bound to discretization errors. The proposed HYFF (HYbrid tractography with Fiber assignment by continuous tracking and Fast marching) is a streamline method which ensures correct directions of tracing by forcing the traced lines to go downstream of the time field generated from FMT.