Jayme Cameron Kosior1,2, Richard Frayne2
1Electrical and Computer Engineering, University of Calgary, Calgary, AB, Canada; 2Seaman Family MR Research Centre, Foothills Medical Centre, Calgary, AB, Canada
A common misconception is that indicator dilution theory cannot be used to derive perfusion parameters such as cerebral blood flow (CBF) and cerebral blood volume (CBV) if tracer recirculation is present in dynamic susceptibility contrast MR perfusion data. Here, we show that it is unnecessary to remove tracer recirculation from DSC-MR data in order to derive perfusion parameters.