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Abstract #1595

Reduction of Physiological Noise Effects in FMRI Phase Time Series

Gisela E. Hagberg1, Marta Bianciardi2, Valentina Brainovich1, Bruno Maraviglia3

1Santa Lucia Scientific Foundation, Rome, Italy; 2LFMI, NINDS, NIH, Bethesda, MD, USA; 3University La Sapienza, Rome, Italy

MRI is a phase sensitive detection system and both magnitude and phase time-series are obtained in an fMRI study. In a previous work it was shown that physiologic noise has a greater impact on phase than magnitude images. It was suggested that large scale fluctuations of the static magnetic field due to respiration and heart beat are the main cause of this difference. In this work we first characterised the effect of physiologic parameters (ECG and respiration) on the magnitude and the phase signal and then investigated the effect of different post-processing methods, including spatial filtering.