Matthew J. Brookes1, Karen J. Mullinger1, Gera Bjrk Geirsdttir1, Claire M. Stevenson1, Richard Bowtell1, Peter G. Morris1
1Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, Nottinghamshire, UK
Simultaneous EEG/fMRI is an attractive means by which to investigate human brain function in vivo. Recent work has shown that the spatial location of changes in electrical neuronal activity can be determined using EEG data recorded during simultaneous fMRI. Further, such source localisation techniques can reduce significantly the level of interference in EEG timecourses caused by the MR scanner. In this work we compare source localisation methods. We show quantitative evidence that both beamformer and dipole fitting can be used for accurate source localisation; however the beamformer is markedly more effective at reducing interference in an EEG time course estimate.
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