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Abstract #1638

Breath Hold Task Significantly Correlates with Cognition Across Run and Visit

Jerod Michael Rasmussen1, Sumiko Abe1, Liv C. McMillan1, Josef Pfeuffer2, Jessica Turner1, Function BIRN3

1University of California, Irvine, Irvine, CA, USA; 2Siemens Medical Solutions;

The hypercapnic breath hold task is a non-invasive measurement of Cerebral Blood Flow (CBF) and has been shown to reduce variance across subjects through calibration. Subject wise correlations between breath hold activity and working memory are calculated across visit and run. Correlations were found to be positive and strong demonstrating the physiological coupling between CBF and the Blood Oxygenation Level Dependent (BOLD) signal. These results suggest confounds of run and visit can be accounted for in a calibrated model.