Deconvolved FMRI Correlates with Source-Localised MEG as a Function of Neural Frequency Oscillation

Johanna M. Zumer¹, Claire M. Stevenson¹, Matthew J. Brookes¹, Sue T. Francis¹, Peter G. Morris¹

BOLD fMRI is widely used for inferring neural activity from the indirect haemodynamic response that it measures. MEG measures direct neuromagnetic effects across time and frequency and recent techniques enable a full spatial-temporal-frequency reconstruction of neural sources. Here, we deconvolved a BOLD response to a 4s visual stimulus with the haemodynamic response function to get an estimate of neural activity from fMRI. We correlated this prediction with the source-localised result from MEG across frequency bands and found a significant negative correlation with lower frequencies (4-25Hz) and a significant positive correlation with high frequencies (52-98Hz).