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Abstract #1699

Acute Blockade of 5HT2a Receptors Reduces Orbitofrontal Cortex Response to Angry and Fearful Faces

Bettina Hornboll1,2, Jon S. Wegener1,2, Olaf B. Paulson1,2, James B. Rowe2,3, Gitte Moos Knudsen2,4, Hartwig Siebner1,2, Julian Macoveanu1,2

1Danish Recearch Center for MR, Copenhagen University Hospital, Hvidovre, Hvidovre, Denmark; 2Center for Integrated Molecular Brain Imaging, Copenhagen, Denmark; 3Department of Clinical Neurosciences, Cambridge University, Cambridge, UK; 4Neurobiology Research Unit,, Copenhagen University Hospital, Copenhagen, Denmark


In 17 healthy volunteers, we used pharmacological functional MRI to