Blood Oxygen Level-Dependent Cardiovascular Magnetic Resonance Imaging (BOLD-CMR) in Assessment of Transmural Perfusion Effect

Jacqueline Allison Flewitt¹, Matthias Voehringer^1,2, Jordin Daniel Green^1,3, Matthias G. Friedrich¹

Blood Oxygen Level Dependant (BOLD) cardiovascular MR imaging can detect perfusion changes in the myocardium and has the potential to detect transmural changes across the myocardium. A study of healthy control subjects and patients with suspected coronary artery disease was conducted using SSFP BOLD sensitive imaging techniques. The signal intensity was calculated during rest and the increase with adenosine infusion. A significant difference between the epicardium and endocardium was detected in the patients whereas no significant difference occurred in the healthy subjects.