Abstract #1763

Cardiac Diffusion Tensor Magnetic Resonance Imaging for High Resolution Reconstruction of Individual Whole Hearts

Patrick William Hales¹, Fleur Mason², Rebecca Burton², Christian Bollensdorff², Martin Bishop³, Gernot Plank³, Peter Kohl², Jurgen Schneider¹

¹Department of Cardiovascular Medicine, Oxford University, Oxford, Oxon, UK; ²Department of Physiology, Anatomy and Genetics, Oxford University, Oxford, Oxon, UK; ³Computational Biology Group, Oxford University, Oxford, Oxon, UK

The 3D Heart project aims to develop an efficient methodology for the acquisition of cardiac anatomical MRI data, DTI data, and histology, and to develop techniques for automated segmentation and registration of these data sets to create high resolution computer models of individual whole hearts. We present here the progress to date of this project, focussing on methodological developments for the acquisition of the high resolution DTI data sets. The challenges posed by the processing and combination of large, multiple data sets into a single comprehensive model are also discussed.