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Abstract #1791

Assessment of Heart Function by Cardiac MR Elastography: Comparison to Left Ventricular Pressure Measurements

Thomas Elgeti1, Michael Laule2, Nicola Kaufels1, Jrg Schnorr1, Uwe Hamhaber3, Dieter Klatt1, Sebastian Papazoglou1, Carsten Warmuth1, Bernd Hamm1, Braun Juergen3, Ingolf Sack1

1Department of Radiology, Charit - University Medicine Berlin, Berlin, Germany; 2Clinic of Cardiology, Charit - University Medicine Berlin, Berlin, Germany; 3Institute of Medical Informatics, Charit - University Medicine Berlin, Berlin, Germany

MR elastography (MRE) is capable to measure myocardial elasticity changes without intervention. The aim of this study was to investigate the correlation between LV-pressure and cardiac MRE-signal. Therefore, MRE was applied to three minipigs displaying individual variations of heart rate, systolic and diastolic pressure and pressure gradients. Tip manometers mounted on catheters were used to directly acquire LV-pressure functions over time. A good correlation of Cardiac MRE with invasively observed LV-pressure changes was observed. Individual variations of LV-pressure differences could be reproduced by MRE.