Abstract #1881

Non-Contrast-Enhanced MRA of the Renal Arteries Using Inflow-Enhanced, Inversion-Recovery BSSFP: Validation Against DSA in a Porcine Model of Renal Artery Stenosis

Thorsten Alexander Bley¹, Christopher Jean Pierre Francois¹, Mark L. Schiebler¹, Oliver Wieben², Naoyuki Takei³, Wei Sun⁴, Mitsuharu Miyoshi³, Jean H. Brittain⁴, Reed F. Busse⁴, Thomas M. Grist¹, Scott B. Reeder¹

¹Radiology, University of Wisconsin - Madison, Madison, WI, USA; ²Radiology and Medical Physics, University of Wisconsin - Madison, Madison, WI, USA; ³MR Applied Sciences Laboratory, GE Healthcare, Tokyo, Japan; ⁴MR Applied Sciences Laboratory, GE Healthcare, Waukesha, WI, USA

This study evaluates an investigational version of the Inhance Inflow IR pulse sequence, a balanced SSFP (bSSFP) based NCE-MRA sequence that is combined with the inflow effects of time of flight MRA for detection and quantification of renal artery stenoses, in a porcine model. Results of three readers who evaluated the degree of surgically created renal artery stenosis in 12 swine were compared to 3D rotational DSA. The NCE-MRA technique produced consistent results, with no technical failures. Good correlation between NCE-MRA and DSA demonstrates the feasibility of this NCE-MRA sequence for assessment of renal artery stenoses.