Abstract #1893

On-Resonant Binomial Pulse Preparation for Magnetization Transfer Contrast Enhanced Coronary Vein Imaging

Christian Torben Stoeck^1,2, Dana C. Peters¹, Yuchi Han¹, Kraig V. Kissinger¹, Beth Goddu¹, Lois Goepfert¹, Warren J. Manning^1,3, Sebastian Kozerke², Reza Nezafat¹

¹Department of Medicine (Cardiovascular Division), Beth Israel Deaconess Medical Center and Harvard, Boston, MA, USA; ²Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland; ³Department of Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA

Off-resonance RF irradiation for magnetization transfer contrast has recently been shown to create an appropriate amount of contrast in coronary vein imaging. In this study, we sought to investigate the use of an optimal binomial pulse for on-resonant magnetization transfer sequences. In the lower range of applied flip angles the on-resonant RF irradiation showed to be superior to off-resonant irradiation, which might be of benefit if the amount of RF energy deposition in tissue is limited.