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Abstract #1905

Platform for Comprehensive Hemodynamic Analysis of 4D PC MRI Data

Elizabeth Janus Nett1, Kevin M. Johnson1, Benjamin R. Landgraf2, Oliver Wieben1,2

1Medical Physics, University of Wisconsin, Madison, WI, USA; 2Radiology, University of Wisconsin, Madison, WI, USA

New approaches for rapid MR imaging have allowed for the in vivo acquisition of volumetric phase contrast images of cine velocity fields for the examination of vascular anatomy and function. It also allows for the derivation of additional hemodynamic parameters such as wall shear stress and pressure gradients. However, the visualization and analysis of thousands of images containing anatomical and functional data pose a significant challenge for clinical work up. We developed and validated a software platform that streamlines hemodynamic measurements from PC VIPR acquisitions, including analysis plug-ins for flow measurements with automatic alignment with respect to vessel orientation and and tools for the derivation of wall shear stress and pressure gradients. Such a platform will be important for the clinical adaptation of 4D PC MRI.