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Abstract #1937

Quantitative Measurement of Bone Marrow Composition and Bone Structure Using Simultaneous Acquisition of Fat Fraction and T2* with Multiple Gradient Echo Images

Eito Kozawa1, Tomoyuki Okuaki2, Waka Saito3, Kaiji Inoue4, Yasuo Sakurai5, Fumiko Kimura6

1Radiology, Saitama Medical University, Hidaka, Saitama, Japan; 2Philips Medical System, Japan; 3Saitama Medical University , Japan; 4Radiology, Japan; 5Central Radiology, Saitama Medical University, Japan; 6Radiology, Saitama Medical University, Saitama, Japan

We illustrate its use for measuring lumbar spine of fat fraction and T2* in normal adults and hematological disease patients with multiple gradient echo images (MGE). Fat fractions of MGE vs. MR spectroscopy (MRS), and T2* vs. aging change were analyzed by linear regression. Fat fraction values of MGE and MRS show very good agreement. T2* values vs. aging change showed negative linear correlation. In conclusion, MR determination of those parameters could be used to assess and diagnose a deficiency in marrow composition and bone structure using fat fraction and T2*.