Abstract #1937

Quantitative Measurement of Bone Marrow Composition and Bone Structure Using Simultaneous Acquisition of Fat Fraction and T2* with Multiple Gradient Echo Images

Eito Kozawa¹, Tomoyuki Okuaki², Waka Saito³, Kaiji Inoue⁴, Yasuo Sakurai⁵, Fumiko Kimura⁶

¹Radiology, Saitama Medical University, Hidaka, Saitama, Japan; ²Philips Medical System, Japan; ³Saitama Medical University , Japan; ⁴Radiology, Japan; ⁵Central Radiology, Saitama Medical University, Japan; ⁶Radiology, Saitama Medical University, Saitama, Japan

We illustrate its use for measuring lumbar spine of fat fraction and T2* in normal adults and hematological disease patients with multiple gradient echo images (MGE). Fat fractions of MGE vs. MR spectroscopy (MRS), and T2* vs. aging change were analyzed by linear regression. Fat fraction values of MGE and MRS show very good agreement. T2* values vs. aging change showed negative linear correlation. In conclusion, MR determination of those parameters could be used to assess and diagnose a deficiency in marrow composition and bone structure using fat fraction and T2*.