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Abstract #1940

Evaluation of Motion Corruption on Image Quality in Micro MRI of Trabecular Bone: Impact on Structural Parameters

Yusuf A. Bhagat1, Michael J. Wald1, Chamith S. Rajapakse1, Hamid Saligheh Rad1, Jeremy F. Magland1, Mary B. Leonard2, Felix W. Wehrli1

1Laboratory for Structural NMR Imaging, Radiology, University of Pennsylvania, Philadelphia, PA, USA; 2Nephrology, Children's Hospital of Philadelphia, Philadelphia, PA, USA

In this work, we aimed to evaluate the robustness of an image evaluation system for trabecular bone (TB) imaging by applying several translational motion trajectories to a relatively motion-free good quality TB image and compared the mean scores (from 4 raters) obtained from the image rating scheme to an objective image sharpness criterion chosen as the normalized gradient squared (NGS). Images demonstrating a poor NGS value (>1% reduction) relative to the original uncorrupted image, can demonstrate a change in the digital topological parameters from 8-24%, thereby conferring substantial weight to an image evaluation system for routinely grading in vivo scans.