Silvia De Santis1, Silvia Capuani2
1Physics Department Sapienza University Rome, Rome, Italy; 2CNR-INFM SOFT, Physics Department Sapienza University Rome, Rome, Italy
Parametric maps based on the mean anomalous exponent (M) and on its anisotropy (A) may offer complementary information compared to conventional DTI-maps. Our aim was to characterize the peculiar water diffusion behavior in calf bone-marrow by means of evaluation at different lipid-to-water ratios. M in 8 months bone marrow sample shows a strong deviation from Gaussian diffusion. This could be due to a more complex water compartmentalization in 8 months bone marrow sample compared to samples characterized by a lower water/fat ratio. M and A maps result less affected by susceptibility and chemical-shift artifacts than the conventional DTI-maps.
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