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Abstract #1958

T1ρ Mapping of Pediatric Epiphyseal and Articular Cartilage

Jared Guthrie Cobb1,2, J. Herman Kan3

1Biomedical Engineering, Vanderbilt University, Nashville, TN, USA; 2Institute of Imaging Science, Vanderbilt University, Nashville, TN, USA; 3Radiology and Radiological Sciences, Vanderbilt Children's Hospital, Nashville, TN, USA

The purpose of this study is to determine feasibility of T1 mapping of pediatric epiphyseal and articular cartilage. Seven volunteers of age 13 2 years were recruited to have T1 mapping performed at the conclusion of their clinical study. T1 contrast was generated using a SL pre-pulse developed by Avison. Regions of interest were placed in non-weight-bearing regions of the sagittal slice in the epiphyseal and articular cartilage. Mean values for T1 in articular cartilage are reported as 65.1 15.4 ms. Epiphyseal cartilage is reported as 49.3 5.2 ms. Epiphyseal and articular cartilage T1 differences may reflect differences in water and glycosaminoglycan composition.