Gabrielle Blumenkrantz1, Julio Carballido-Gamio2, Charles E. McCulloch3, John A. Lynch3, Thomas M. Link2, Sharmila Majumdar1
1Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA; 2Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, USA; 3Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA, USA
The purpose of this study is to [1] examine changes in MR knee cartilage parameters including thickness, T2, and spatial distribution of cartilage T2 and [2] examine whether these baseline MR parameters predict change in knee pain over two years. The results indicate a significant decrease in cartilage thickness over two years. Of all MR parameters evaluated (including cartilage thickness and mean T2), only the baseline entropy of cartilage T2 was significantly associated with longitudinal rate-of-change in pain.
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