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Abstract #1978

Validation of Cartilage Thickness Calculations Using Indentation Analysis

Matthew F. Koff1, LeRoy Chong2, Patrick Virtue3, Dan Chen4, Timothy Wright4, Hollis Potter1

1Department of Radiology and Imaging, Hospital for Special Surgery, New York, NY, USA; 2Department of Diagnostic Radiology, Changi General Hospital, Singapore; 3GE Healthcare, Waukesha, WI, USA; 4Department of Biomechanics, Hospital for Special Surgery, New York, NY, USA

Magnetic resonance imaging (MRI) can be used for non-invasive quantification of cartilage distribution within a joint. A limited number of cartilage thickness validation studies have been performed. The goal of this study was to perform a matching point-to-point validation of indirect cartilage thickness calculations from MR images with direct cartilage thickness measurements using biomechanical indentation. A phantom was used to register data from the image and the indentation coordinate systems. Differences between the methods of cartilage thickness measurement were 0.047+/-0.218 mm (mean+/ This study will aid in validating a tool for clinical evaluation of in-vivo cartilage thickness.