Abstract #2021

Oxygen-Enhanced MR Imaging: Compared Efficacy of Pulmonary Functional Loss Assessment and Clinical Stage Classification in Asthmatics with Quantitatively Assessed CT

Yoshiharu Ohno¹, Hisanobu Koyama¹, Keiko Matsumoto^1,2, Yumiko Onishi¹, Daisuke Takenaka¹, Munenobu Nogami^1,3, Nobukazu Aoyama⁴, Hideaki Kawamitsu⁴, Kazuro Sugimura¹

¹Radiology, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan; ²Radiology, Yamanashi University, Shimokatou, Yamanashi, Japan; ³Division of Image-Based Medicine, Institute of Biomedical Research and Innovation, Kobe, Hyogo, Japan; ⁴Division of Radiology, Kobe University Hospital, Kobe, Hyogo, Japan

Oxygen (O2) -enhanced MRI as well as hyperpolarized noble gas MR imaging have been proposed as useful procedures for evaluation of morphological changes or regional pulmonary functional changes. However, the literature shows no publications dealing with prospective and direct comparison of the capability of quantitatively assessed CT and of O2-enhanced MRI for pulmonary functional loss assessment and clinical stage classification in asthmatics. The purpose of the study reported here was to prospectively and directly compare the efficacy of O2-enhanced MRI and quantitative CT for functional loss assessment and clinical stage classification in asthmatics.