Vikas Gulani1, Katherine L. Wright2, Yu-Hua Fang2, Stephen R. Yutzy2, Jeffrey L. Duerk1,2, Mark A. Griswold1,2, Raymond F. Muzic1,2
1Department of Radiology, Case Western Reserve University/University Hospitals of Cleveland, Cleveland, OH, USA; 2Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA
Free breathing, time resolved contrast enhanced MR angiography of the renal vessels was performed with time resolved imaging with stochastic trajectories (TWIST). A kinetic model of perfusion was developed and used to fit ROI data from the renal cortex and medulla. The fit model parameters were used to calculate perfusion in these regions. Half of the standard dose of Gadolinium-DTPA was used (0.05 mmol/kg). This work shows that a single, time resolved angiography data with very low dose Gadolinium can be used to obtain both MRA and perfusion measurements.