Abstract #2041

Measurement and Comparison of T1 Relaxation Times in Native and Transplanted Kidney Cortex

Yin Huang¹, Nathan Artz¹, Zhifei Wen¹, Elizabeth Sadowski^1,2, Sean Fain^1,2

¹Medical Physics, University of Wisconsin-Madison, Madison, WI, USA; ²Radiology, University of Wisconsin-Madison, Madison, WI, USA

An interactive segmentation method was developed to measure the T1 of renal cortex on a pixel-by-pixel basis. Native (22 kidneys) and transplanted (11 kidneys) kidneys with a wide range of kidney functions were analyzed to determine whether there is a difference between the native and transplant T1 values. The average T1 of cortical tissue in native kidneys is 100247.4 (meanstandard deviation) msec and the average T1 of cortical tissue in transplanted kidneys is 1180 110.6 msec. This difference was found to be statistically significant (p = 0.0022).