Yin Huang1, Nathan Artz1, Zhifei Wen1, Elizabeth Sadowski1,2, Sean Fain1,2
1Medical Physics, University of Wisconsin-Madison, Madison, WI, USA; 2Radiology, University of Wisconsin-Madison, Madison, WI, USA
An interactive segmentation method was developed to measure the T1 of renal cortex on a pixel-by-pixel basis. Native (22 kidneys) and transplanted (11 kidneys) kidneys with a wide range of kidney functions were analyzed to determine whether there is a difference between the native and transplant T1 values. The average T1 of cortical tissue in native kidneys is 100247.4 (meanstandard deviation) msec and the average T1 of cortical tissue in transplanted kidneys is 1180 110.6 msec. This difference was found to be statistically significant (p = 0.0022).