Abstract #2059

Intra-Voxel Incoherent Motion MRI in Rodent Model of Diethylnitrosamine-Induced Liver Fibrosis

Yue Zhang^1,2, Ning Jin^2,3, Jie Deng², Tamuna Chadashvili², Yang Guo², Guang-yu Yang⁴, Andrew Christian Larson^2,5

¹Department of Bioengineering, University of Illinois at Chicago, Chicago, IL, USA; ²Department of Radiology, Northwestern University, Chicago, IL, USA; ³Department of Biomedical Engineering, Northwestern University, Chicago, IL, USA; ⁴Department of Pathology, Northwestern University, Chicago, IL, USA; ⁵Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL, USA

Intra-voxel incoherent motion (IVIM) imaging permits in vivo quantification of diffusion and perfusion. The purpose of our study was to investigate the relationship between hepatic IVIM measurements and diethylnitrosamine-induced fibrosis levels in the Wistar rat model.