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Abstract #2068

Effects of Extracellular Hepatobilliary Gadolinium Based Contrast Agents on Apparent Diffusion Coefficient

Manuel Rodriguez1,2, Masoud Shiehmorteza2, Karthik Ganesan2, Claude Sirlin2

1Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA; 2Radiology, Liver Imaging Group University of California San Diego, San Diego, CA, USA

The purpose of this study is to evaluate the effects of mixed extracellular hepatobilliary gadolinium based contrast agents (GBCA) on diffusion-weighted (Dw) imaging and apparent diffusion coefficient (ADC) values in patients with focal hepatic lesions. Twelve patients underwent Dw imaging and ADC values were acquired before and after the administration of mixed extracellular hepatobilliary GBCA. Our study showed that the administration of mixed extracellular hepatobilliary GBCA results in a mild but statistically significant elevation in hepatic ADC.