Cross-Validation of Magnetic Resonance Elastography and Ultrasound-Based Transient Elastography in Phantom Materials

Jun Chen¹, Jennifer Oudry², Kevin Glaser¹, Vronique Miette², Laurent Sandrin², Richard Ehman¹

Currently Magnetic resonance Elastography (MRE) and Ultrasound-based Transient Elastography (UTE) have shown usefulness for diagnosing hepatic fibrosis. Comparisons between them has been done in-vivo, but lacked the control necessary to assess the agreement of the fundamental mechanical properties measured by the two techniques. This study directly compared the stiffness values measured by MRE and UTE on a set of well-characterized phantoms, demonstrated excellent correlation in measurement of shear stiffness, and no evidence of systemic differences.