MR Manifestations of Ovarian Clear Cell Adenocarcinomas: A Pictorial Review

Kenji Matsuzaki¹, Mayumi Takeuchi¹, Hiromu Nishitani¹

MR manifestations of ovarian clear cell adenocarcinomas were reviewed. Unilocular large cystic mass containing serous or hemorrhagic fluid with contrast-enhanced mural nodules, which show very high intensity on DWI with low ADC (1.10 +/- 0.21, n=10), is the typical finding. Various histologic subtypes may be admixed in a tumor and not correlate with imaging features. Clear cell adenocarcinoma may arise from endometriosis in relatively younger women, and prognosis is poor in the advanced stage disease. To detect mural nodules is important for the early diagnosis, and subtraction imaging is helpful to evaluate small nodules in hyperintense cyst on T1WI.