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Abstract #2108

Effect of B1 Inhomogeneity-Correction on T1-Uniformity in Breast MRI at 1.5 Tesla: Preliminary Results

Riham H. El Khouli1, David Michael Thomasson1, Yuxi Pang2, David Bluemke1

1Radiology and Imaging Sciences, National Institutes of Health, Bethesda, MD, USA; 2Philips Healthcare, Cleveland, OH, USA

It has been shown that b1 inhomogeneity can affect quantitative evaluation of dynamic contrast enhanced MRI of the breast at high fields, we show that it is also important at 1.5 Tesla. B1 field maps can correct for spatially varying flip angles and consequently improve T1 maps and subsequent Gd concentrations calculated from the baseline T1 Since B1 terms are used in calculating the T1 map and in the subsequent calculation of Gd concentration, these measures may be more robust in determining simple enhancement ratios as well as the more sophisticated pharmaco-kinetic based permeability maps.