Michael A. Jacobs1,2, Li Pan3, Katarzyna Macura4, Ronald Ouwekerk4, Antonio C. Wolff2, Vered Stearns2, Ihab Kamel4, Nouha Salibi3, Wilhelm Horger5, David Bluemke4, Christine Lorenz3
1The Russell H. Morgan Department of Radiology and Radiological Science , The Johns Hopkins University School of Medicine, Baltimore , MD , USA; 2Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; 3Siemens Corporate Research, Inc., Baltimore, MD, USA; 4The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USA; 5Siemens AG Healthcare Sector, Erlangen, Germany
The ability to diagnose metastatic disease without radiation would be an advancement in the initial work-up of cancer[1]. The purpose of this study was to investigate the potential use of a novel whole body diffusion weighted imaging (WB-DWI) method coupled magnetic resonance spectroscopy (MRS) for the detection and monitoring of metastatic disease in patients and transition to 3T.