M. A. Malikova1, Jaroslaw Nicholas Tkacz2, Adam Yaakil2, Priscilla Slanetz3, Hernan Jara2
1Surgery, Boston University Medical
Center, Boston, MA, USA; 2Radiology, Boston University Medical
Center, Boston, MA, USA; 3Radiology, Beth Israel Medical Center,
Boston, MA, USA
We have developed a quantitative MRI technique for mapping the longitudinal-to-transverse relaxation times ratio (T1/T2) of benign and malignant breast lesions. This technique gives reliable quantitative results and produces high image quality on T1, T2, and T1/T2 maps, as tested on 20 female subjects with known or suspected lesions proven by biopsy and pathologic correlation. In our small series, there is a statistically significant difference in the T1/T2 ratios of benign and malignant breast lesions using this technique.