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Abstract #2194

Combined Proton and HP 3He Oxygen Partial Pressure Mapping for the Evaluation of Acute Respiratory Distress Syndrome

Elise Bannier1, Katarzyna Cieslar1, Sophie Gaillard1, Abdulrazzaq Sulaiman1, Emmanuelle Canet-Soulas1, Yannick Crmillieux1

1Universit de Lyon, CREATIS LRMN, Lyon, France

Acute Respiratory Distress Syndrome (ARDS) can result from multiple factors such as pulmonary infection, gas inhalation or drowning. In this work, proton and hyperpolarized 3He MRI were applied in a rabbit model of ARDS. Alteration of ventilation and gas exchange were observed and quantified using both oxygen partial pressure and oxygen depletion rate maps and compared to inflammation extent on proton images.