Meeting Banner
Abstract #2221

Evaluation of Computer Aided 3D Parametric Analysis of MR-Mammography for Follow-Up Assessment of Malignant Lesions Under Primary Systemic Therapy

Lale Umutlu1, Stefan Maderwald1, Till A. Heusner1, Sherko Kuemmel2, Rainer Kimmig2, Elke Hauth1, Michael Forsting1, Thomas C. Lauenstein1

1Department of Diagnostic and Interventional Radiology and Neuroradiology, University Hospital Essen, Essen, NRW, Germany; 2Department of Gynaecology and Obstetrics, University Hospital Essen, Essen, NRW, Germany

Apart from non-melanoma skin cancer, breast cancer is currently the most common cancer type among women. In case of multricentric or inoperable tumor manifestation neoadjuvant chemotherapy is used for preoperative tumor size reduction. Hence, the evaluation of early treatment response is an inevitable issue in primary systemic therapy. Computer aided detection systems provide a fast and reliable determination of tumor volume, as well as changes in further, important follow-up markers, by means of contrast kinetics, vascular permeabilitiy and extracellular volume fraction. Thus, CAD systems enable valid assessment of early treatment response under neoadjuvant chemotherapy.