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Abstract #2343

Single Voxel Spectroscopy in Different Regions of Human Brain at 7 T

Malgorzata Marjanska1, Edward J. Auerbach1, Pierre-Francois Van de Moortele1, Gregor Adriany1, Michael Garwood1

1Center for Magnetic Resonance Research and Department of Radiology, University of Minnesota, Minneapolis, MN, USA

Proton Magnetic Resonance Spectroscopy provides a noninvasive way to investigate in vivo neurochemical abnormalities of many brain disorders. Each observable metabolite can potentially provide unique information about brain biochemistry and be a biomarker for brain disorders which will facilitate diagnosis and treatment. Spectra of exceptional quality have been obtained and quantified previously at 7 T from human occipital lobe. However, for many brain disorders the neurochemical abnormalities are not expected to occur in occipital lobe, but in other brain structures. In this project, we investigate the ability to obtain high quality 7 T spectra from different brain regions.