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Abstract #2475

Experimental Setup for DNP Spectroscopy and Variable Field Proton Electron Double Resonance Imaging

Alexandre Samouilov1, Eric Kesserling1, Sergey Petryakov1, Keerthi Shet1, Ziqi Sun1, David J. Lurie2, Jay L. Zweier1

1Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA; 2Department of Bio-Medical Physics and Bio-Engineering, University of Aberdeen, Aberdeen, UK

A variable field system capable of performing DNP spectroscopy and variable field PEDRI with NMR detection at any magnetic field in the range 0 - 0.38 T is described. The system is built around a clinical MRI electromagnet. To obtain EPR spectral characteristics, partial cancellation of the detection NMR field is required to alter the evolution EPR field at which the electron paramagnetic resonance excitation is achieved. The addition of resistive field cancellation coils in the gap of the primary magnet provides this fast offset in the range of 00.1 T.