Abstract #2508

Assessment of Hepatic Fibrosis in Liver Transplant Patients Using MR Elastography - Preliminary Results

Patrick Asbach¹, Dieter Klatt¹, Carsten Kamphues², Peter Neuhaus², Jrgen Braun³, Ingolf Sack¹

¹Department of Radiology, Charit University Hospital, Berlin, Germany; ²Department of General-, Visceral- and Transplantation Surgery, Charit University Hospital, Berlin, Germany; ³Department of Medical Informatics, Charit University Hospital, Berlin, Germany

Following liver transplantation viral re-infection of the graft frequently occurs and progression of fibrosis advances more quickly in the transplanted liver. The aim of the study was to investigate the potential of MR-elastography (MRE) in detecting liver fibrosis in transplant patients. MRE was applied to 10 patients with biopsy-proven liver fibrosis. Significant differences were found between the viscoelasticity of the liver of low-grade fibrosis patients ( = 3.21 0.27; mean SD) and high-grade fibrosis patients ( = 5.19 1.27). MR elastography has the potential to non-invasively detect liver fibrosis in transplant patients.