Max Oskar Khler1, Julia Enholm1, Charles Mougenot2,3, Bruno Quesson3, Chrit T. W. Moonen3
1Philips Healthcare, Vantaa, Finland; 2Philips Healthcare, France; 3Laboratory of Molecular and Functional Imaging, University of Bordeaux 2, Bordeaux, France
A binary feedback control of the sonication duration was implemented and validated in-vivo on 11 male pigs. The feedback control reduced the outcome variability and the induced thermal lesion size was closer to that desired. The use of binary feedback in conjunction with volumetric ablation did not reduce the energy efficiency and the resulting thermal lesion also remained as homogeneous and well-defined as for non-feedback volumetric ablation.