Kagayaki Kuroda1,2, Makoto Obara1,3, Marc Van Cauteren4, Masatoshi Honda5, Yutaka Imai5
1Graduate School of General Science and Technology, Tokai University, Hiratsuka, Kanagawa, Japan; 2Medical Device Development Center, Foundation for Biomedical Research and Innovation, Kobe, Hyogo, Japan; 3Medical Systems , Philips Electronics Japan, Tokyo, Japan; 4Medical Systems, Philips Electronics Japan, Tokyo, Japan; 5Department of Radiology, Tokai University, Isehara, Kanagawa, Japan
Temperature dependences of relaxation times in the individual fatty acid components in various samples in vitro were examined at 11T to provide a basis for quantitative temperature imaging of adipose tissues such as included in breast. T1 of both methylene chain and terminal methyl had linear relationships with temperature (r > 0.98), but the temperature coefficient for the two components differed significantly; those in five bovine fat samples were 11.6 0.42 ms/deg C for methylene and 31.2 3.92 ms/deg C for methyl. Numerical simulations based on the difference demonstrated that the inconsistency in the fatty acid component ratios for temperature calibration and estimation may cause considerable errors.