Abstract #2561

MR Validation and Quantification of TACE Treatment Through Direct Visualization of Ethiodol with Chemical Shift Based Water-Fat Imaging

Eric M. Bultman¹, Catherine D. Hines¹, Walter F. Block^1,2, Scott B. Reeder^1,3

¹Department of Biomedical Engineering, University of Wisconsin, Madison, WI, USA; ²Department of Medical Physics, University of Wisconsin, Madison, WI, USA; ³Department of Radiology, University of Wisconsin, Madison, WI, USA

Transcatheter arterial chemoembolization is frequently used to treat unresectable malignant neoplasms of the liver such as HCC. Traditionally, TACE delivers a bolus of chemotheraputic agents, suspended in ethiodol, through a hepatic arterial catheter. In this work, we explore the feasibility of using IDEAL fat-water separation to exploit the fat-based contrast provided by ethiodol, allowing for visualization of the region of TACE treatment via MR imaging. Results demonstrate the equivalence of IDEAL fat-only imaging to follow-up CT scan with regards to quality of visualization, while the IDEAL fat fraction may allow for monitoring of ethiodol dose delivery during the procedure.